Recommended Guidelines

American College of Obstetricians and Gynecologists (ACOG; 2023)

Up-to-Date Guidelines (2023; paywalled)

Treatment of premenstrual syndrome and premenstrual dysphoric disorder - UpToDate

Or, see first-line treatment guidelines included in the GnRHa paper discussed below.

Advanced Guidelines from the CLEAR Lab: Use of GnRHa with Stable Hormone Addback for Treatment-Resistant PMDD

Our lab has recently contributed a clinical guideline with practical handouts and other clinical resources to guide psychiatrists and other physicians in evidence based care for PMDD and particularly in the safe long-term use of GnRHa + stable addback for PMDD. The approach is based on meta-analytic evidence for benefit in clinical trials, as well as recent evidence that patients with PMDD can tolerate stable hormone addback over the long term (after an initial temporary symptom flare).

GnRH Analogs in Premenstrual Dysphoric Disorder: Review and Practical Guideline

<aside> 👉 What's Stopping Us? Using GnRH Analogs With Stable Hormone Addback in Treatment-Resistant Premenstrual Dysphoric Disorder: Practical Guidelines and Risk-Benefit Analysis for Long-term Therapy

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